About – bachbtrial.org.uk

About the BACHb research trial

BACHb will in essence conduct two clinical trials at the same time to determine the effectiveness of HFNC, one in moderate bronchiolitis and one in severe bronchiolitis.

How will the research be conducted and what will happen during the trial

Infants with moderate bronchiolitis will be randomly allocated to start either high flow nasal cannula (HFNC) or humidified standard oxygen (HSO), and those with severe bronchiolitis to either HFNC or Continuous Positive Airway Pressure (CPAP). All other treatment decisions will be left to the clinical team.

Key facts

1508 babies with acute bronchiolitis

50 NHS hospitals children’s emergency departments and wards

Throughout the United Kingdom over 3 years

The research will finish in 2026

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© Imperial College London 2023

This study is funded by the NIHR Health Technology Assessment programme (17/136/02). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.